Revanesse (リバネッセー) - Cross Linked Hyaluronic acid

What is Revenesee?

Revanesse® is a new biodegradable non-animal based clear Hyaluronic acid gel. Revanesse® is best used to fill superficial imperfections in the dermis, such as fine lines, forehead wrinkles, crow's feet, perioral lines, small nasolabial folds, and glabeller lines. Revanesse® will break down naturally in your body after about 6 months without leaving any harmful by-products.

CoPolymer Advantage

Over time, skin loses its natural abundance of hyaluronic acid, which is a natural occurring acid found in the skin and is the key component of the extra cellular matrix. As the newest (HA) hyaluronic acid based filler, The Revanesse family of products provides doctors and patients with a dermal filler that is easy to inject, rejuvenates the skin and contains the highest concentration of HA available.

Cross linked HA is Hydrophilic and can hold up to 10,000 times its mass in water. When cross linked HA is injected into the skin it pulls moisture away from already damaged skin, causing dehydration. The patient is therefore left with an implant that drains the moisture for the duration of its time in the dermis. In order to avoid this problem, we have created a copolymer, a mix made of cross lined HA and non cross linked HA. The addition of non cross linked Hyaluronic acid provides moisture to surrounding tissue while augmentation is achieved through the cross linked HA. The result is a product that not only fills in lines and wrinkles but rejuvenates while hydrating and moisturizing the skin.

Before and After Treatment

• Before the treatment, skin must be clean and any make up or cosmetics should be removed, preferably using an astringent or facial cleansing lotion and cold water to ensure that pores are not dilated. In order to avoid increased bleeding and swelling at the injection site, it is strongly advised that non steroidal antiinflammatories (Advil, Aspirin), Vitamin E or blood thinners are avoided one week prior to treatment.
• After the treatment, facial movements should be kept to a minimum and the face should be relaxed. It is strongly recommended that there be no exposure to extreme heat (sauna, bath) for at least 2 weeks after the treatment. This can cause a shorter life span of the implant as it may cause the hyaluronic acid to breakdown. Some side effects may include temporary swelling of the injection site and/or an inflammatory reaction of the skin, often with pain from pressure, lasting up to one week. Persistence of side effects should be reported to the physician immediately.

Safety

Revanesse, Revanesse Ultra and Redexis are completely synthetic in nature, meaning that the chances of allergic reactions are very rare. Since they contain no animal products (bovine collagen or HA from rooster combs) there is no risk of transmitting diseases. Our Revanesse products can be used without worry of adverse reactions or the need for skin testing.

The hyaluronic acid found in our dermal fillers is naturally integrated into the tissue, allowing for the passage of vital nutrients, oxygen and hormones. Since cells are able to pass between the fragments of the gel, your skin will look healthy and natural.

Because the Revanesse® product line consists of non-permanent fillers, clients can re-assess their needs and alter or continue their course of treatments as desired.